What is Cartrophen?
Cartrophen (Pentosan Polysulfate Sodium) is classified as a Disease Modifying Osteoarthritis Drug (DMOAD) that works via several mechanisms to help maintain joint health and preserve joint cartilage. Approximately 80% of pets will respond positively, with a reduction in pain and lameness, followed subsequently with improvements in activity and well-being.
How does it work?
- Acts directly on the joint to reduce inflammation, thereby reducing joint pain and enzymatic cartilage breakdown
- Improves synovial fluid quantity and quality, which acts to lubricate the joints
- Stimulates the production of new cartilage within the joint
- Stimulates the production of anti-oxidants, which block damaging free radicals
How is it administered?
Cartrophen is administered via an injection under the skin (like a vaccination) once a week for 4 doses. This series of 4 injections can be completed once per year or up to 3 times per year depending on the severity of the arthritis.
Alternatively, single injections can be given at more frequent intervals:
- Once per month
- Once every 3 months
Is it safe?
Cartrophen has a long history of use in veterinary medicine (over 20 years) and has a very low incidence of side effects. Of those that are reported, most are mild and transitory. It is also safe to use concurrently with other medications such as non-steroidal anti-inflammatory drugs (NSAIDs).